I got this question on the “How to Avoid Pitfalls in Schema Upgrade with Percona XtraDB Cluster (PXC)” webinar and wanted to answer it in a separate post. Will RSU have an effect on GTID consistency if replication PXC cluster to another cluster? Answer for this: yes and no . Galera assigns its own GTID for the operations, replicated to all nodes of the cluster. Such operations include DML ( INSERT/UPDATE/DELETE ) on InnoDB tables and DDL commands, executed with default TOI method. You can find more details on how GTIDs work in the Percona XtraDB Cluster in this blog post . However, DDL commands, executed with RSU method, are applied locally and have their own, individual, GTID. Let’s set up a replication between two PXC clusters and see how it works. First, let’s use the default wsrep_osu_method TOI and create three tables on each node of the source cluster: node1> create table toi1(id int) engine=innodb; Query OK, 0 rows affected (0,08 sec) node1> show ...